He aha nā mea hoʻolālā plarmacological?

Ma Pharmacology, nā mea i hoʻopiliʻia e hoʻopiliʻia mai nā mea maʻalahi, i hoʻohana pinepineʻia i nā huahana o nā mea paʻakikī.

He mea nui nā intermediates i ka hoʻomohalaʻana i ka lāʻau lapaʻau a me ka hana hana no ka mea e hoʻoikaika ai lākou i nā mea kanu, a hoʻonui i nā uku, a hoʻonui i ka uku o ka lāʻau lapaʻau. ʻAʻohe o nā intermediatesʻaʻohe mea i hanaʻia a iʻole he meaʻona paha a no lailaʻaʻole hiki ke kūpono no ka hoʻohanaʻana i ke kanaka.

Hoʻokomoʻia nā intermediates i ka wā o ka synthesis o nā mea waiwai a me nā mea waiwai e loaʻa ai nā hopena i nā lāʻau lapaʻau. ʻO APIS nā'āpana o nā lāʻau lapaʻau a hoʻoholo i ka maikaʻi, palekana a me ka pono o nā lāʻau lapaʻau. ʻO ka API ka manawa maʻamau e pili ana i nā kumuwaiwai a iʻole nā ​​kumuwaiwai kūlohelohe a me nā mea e hoʻoikaika ai a me kaʻaeʻana ma mua o ka hoʻohanaʻana i ke kanaka.

ʻO kaʻokoʻa nui ma waena o nā intermediates a me Apis ka mea i hoʻopiliʻia e pili ana i ka hana o Apis. ʻO nā hana a me nā hana o nā intermediates he maʻalahi aʻoi aku ka maʻalahi,ʻoiai ua paʻakikī nā hana lāʻau a me nā hana maʻamau. ʻO nā mea i hoʻopiliʻia i nā koi respedistory a me ka hōʻoia maikaʻiʻana,ʻoiaiʻo APis ke kumuhana e pili ana i nā kūlana regulatory a me ka mana maikaʻi.

Hoʻohana nuiʻia nā intermediates i nā mahina likeʻole a me nāʻoihana e like me nā mea e like me nā mea kanu maikaʻi, biotechnotnothers. ʻO nā interdediates e ulu mau ana a hoʻonui i ka wā e hiki mai ana o nāʻano hou a me nāʻano hou, e like me keʻano o ka chiral, etc.

ʻO nā intermediates ka backbone o ka lākā o kēia wā e like me kā lākou e hiki ai i ka synthesis a me ka hanaʻana o nā apis a me nā lāʻau lapaʻau. Hoʻokomoʻia nā intermediates i ke kīʻana i ka hoʻololiʻana, a me keʻano hana a me ke komoʻana i ka lāʻau lapaʻau, e hoʻomaikaʻi ana i ka maikaʻi o ka lāʻau lapaʻau maikaʻi a me ka hana.